Kansas (27-7, 13-5) ranked #4 in the final regular season AP Poll.
Penn (24-8, 12-2) comes in unranked.
The Quakers are coached by Steve Donahue, who is 48-40 in his third season at Penn. Donahue is 248-254 in 17 seasons overall, with previous stops at Cornell and Boston College.
The Jayhawks lead the all-time series against the Quakers, 3-0.
Bill Self is 34-13 at Kansas in the NCAA Tournament, and KU is 104-45 all-time in NCAA Tournament games.
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